Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990972 | 0.90 | MEN1 (0.46) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991097 | 0.89 | CCR9 (0.37) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8991328 | 0.89 | ALDH1A1 (0.44) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991238 | 0.89 | AURKA (0.40) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8991129 | 0.83 | PDE4A (0.41) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8991288 | 0.81 | MEN1 (0.40) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991134 | 0.80 | GAA (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991286 | 0.79 | GAA (0.41) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991244 | 0.79 | PDE4A (0.40) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991012 | 0.78 | XDH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |