Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 6/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991126 | 0.88 | RET (0.36) | RETKDRFLT3MET | |
| SCHEMBL8991176 | 0.88 | XDH (0.31) | — | |
| SCHEMBL8991298 | 0.81 | RET (0.33) | RETKDRTLR7P2RY1 | |
| SCHEMBL8991290 | 0.80 | RET (0.33) | RETKDRMEN1NPC1NR2F2 | |
| SCHEMBL8991170 | 0.80 | RET (0.31) | RETKDRMEN1NPC1NR2F2 | |
| SCHEMBL8991262 | 0.79 | ADK (0.35) | FLT3AURKARPS6KB1P2RY1 | |
| SCHEMBL8991066 | 0.78 | ALDH1A1 (0.44) | MEN1NPC1RAB9AKMT2ATLR7 | |
| SCHEMBL8991361 | 0.78 | MEN1 (0.46) | MEN1NPC1NR2F2RAB9AKMT2A | |
| SCHEMBL8991164 | 0.76 | LRRK2 (0.40) | RETMEN1NPC1NR2F2RAB9A | |
| SCHEMBL8991288 | 0.76 | MEN1 (0.40) | MEN1NPC1NR2F2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |