Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990936 | 0.88 | ADK (0.33) | ADKFLT3P2RY1PDE4APDE4B | |
| SCHEMBL8991287 | 0.86 | FLT3 (0.40) | FLT3ENPP1 | |
| SCHEMBL8991346 | 0.84 | PDE4A (0.40) | ADKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7699597 | 0.81 | ADK (0.35) | ADKFLT3P2RY1MKNK1MKNK2 | |
| SCHEMBL7699595 | 0.80 | ADK (0.33) | ADKFLT3P2RY1MKNK1MKNK2 | |
| SCHEMBL8991249 | 0.80 | ADK (0.33) | ADKFLT3P2RY1ENPP1 | |
| SCHEMBL8991178 | 0.79 | RET (0.31) | FLT3P2RY1AURKARPS6KB1 | |
| SCHEMBL8991143 | 0.78 | HDAC1 (0.46) | PDE4APDE4BPDE4CPDE4DAURKA | |
| SCHEMBL8991397 | 0.78 | PDE4A (0.51) | FLT3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991078 | 0.76 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |