Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991519 | 0.88 | GAA (0.44) | MTNR1A | |
| SCHEMBL8991489 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BPSEN1PTGESALOX5 | |
| SCHEMBL28697364 | 0.74 | ALDH1A1 (0.46) | MTNR1A | |
| SCHEMBL11172488 | 0.73 | PTPRB (0.58) | — | |
| SCHEMBL28774955 | 0.73 | PTPRB (0.50) | — | |
| SCHEMBL9402671 | 0.72 | PTPN11 (0.54) | MTNR1A | |
| SCHEMBL9402875 | 0.72 | PTPN11 (0.54) | MTNR1A | |
| SCHEMBL9402538 | 0.72 | PTPN11 (0.54) | MTNR1A | |
| SCHEMBL22438874 | 0.70 | PTPN11 (0.55) | — | |
| SCHEMBL22439018 | 0.70 | PTPN11 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516227-B1 | Dry analytical element for lithium assay | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5245021-A | Lithium carbonate analysis | EASTMAN KODAK COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5188802-A | Containing dye derivative of 14-crown-4 ether; colorimetric analysis | EASTMAN KODAK COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0516227-A2 | Dry analytical element for lithium assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516226-A1 | Novel 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |
| US-5132436-A | Intermediates for making 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-07-21 | — | — | US | disclosed |