Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | PTPRG | P23470 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991674 | 0.88 | MTNR1A (0.49) | MTNR1A | |
| SCHEMBL8991579 | 0.79 | GAA (0.45) | GAAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL11172488 | 0.77 | PTPRB (0.58) | PTPN1PTPRCPTPN2PTPRBPTPRG | |
| SCHEMBL28774955 | 0.77 | PTPRB (0.50) | PTPN1PTPRCPTPN2PTPRBPTPRG | |
| SCHEMBL7622744 | 0.75 | PTGER1 (0.43) | GAAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28123736 | 0.74 | PTPN1 (0.53) | PTPN1PTPRCPTPN2PTPRBPTPRG | |
| SCHEMBL7541915 | 0.73 | CETP (0.52) | GAAPTPN1PTPRCCETPMBOAT4 | |
| SCHEMBL7537786 | 0.73 | CETP (0.52) | GAAPTPN1PTPRCCETPMBOAT4 | |
| SCHEMBL28375679 | 0.73 | HTR1A (0.65) | GAAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10956404 | 0.73 | HTR1A (0.65) | GAAPTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516227-B1 | Dry analytical element for lithium assay | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5245021-A | Lithium carbonate analysis | EASTMAN KODAK COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5188802-A | Containing dye derivative of 14-crown-4 ether; colorimetric analysis | EASTMAN KODAK COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0516227-A2 | Dry analytical element for lithium assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516226-A1 | Novel 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |