Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991579 | 0.87 | GAA (0.45) | CCR5LMNAPTGER1PTGER4PTGER3 | |
| SCHEMBL8991674 | 0.81 | MTNR1A (0.49) | MTNR1APTGESALOX5PPARGPSEN1 | |
| SCHEMBL1244579 | 0.70 | MAOB (0.51) | PTGESALOX5PPARGLMNAC5AR1 | |
| SCHEMBL28476407 | 0.70 | MAOB (0.51) | ALOX5PPARGLMNA | |
| Tetradecane SCHEMBL28375680 | 0.69 | SLC6A2 (0.57) | LMNA | |
| SCHEMBL9402747 | 0.68 | PTPN11 (0.64) | — | |
| SCHEMBL9402829 | 0.68 | PTPN11 (0.64) | — | |
| SCHEMBL9402749 | 0.68 | PTPN11 (0.64) | — | |
| SCHEMBL11046795 | 0.68 | MAOB (0.47) | PPARGGGPS1 | |
| SCHEMBL28330023 | 0.68 | ALOX5 (0.54) | ALOX5PPARGCCR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516227-B1 | Dry analytical element for lithium assay | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5245021-A | Lithium carbonate analysis | EASTMAN KODAK COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5188802-A | Containing dye derivative of 14-crown-4 ether; colorimetric analysis | EASTMAN KODAK COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0516227-A2 | Dry analytical element for lithium assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516226-A1 | Novel 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |
| US-5132436-A | Intermediates for making 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-07-21 | — | — | US | disclosed |