SCHEMBL8992127

SCHEMBL8992127

[c]1nnoc1-c1cccnn1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GOT1 P17174 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2038692 0.74 KDM4E (0.50)
SCHEMBL1456807 0.71 GOT1 (0.46) GOT1
SCHEMBL30792004 0.71 GOT1 (0.46) GOT1
SCHEMBL29442588 0.71 GOT1 (0.46) GOT1
SCHEMBL317129 0.67 GOT1 (0.32) GOT1
SCHEMBL13911004 0.67 GOT1 (0.42) GOT1
SCHEMBL3747597 0.65
SCHEMBL5420484 0.65 GOT1 (0.31) GOT1
SCHEMBL6218508 0.64 KDM4E (0.30)
SCHEMBL5012599 0.64 GOT1 (0.31) GOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567717-A COMBATTING PICORNAVIRUSES STERLING WINTHROP, INC. (US) 1996-10-22 US disclosed
US-5514679-A TREATMENT OF PICORNAVIRUS INFECTIONS STERLING WINTHROP INC. (US) 1996-05-07 US disclosed