Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792004 | 0.71 | GOT1 (0.46) | GOT1DHODH | |
| SCHEMBL29442588 | 0.71 | GOT1 (0.46) | GOT1DHODH | |
| SCHEMBL1456807 | 0.71 | GOT1 (0.46) | GOT1DHODH | |
| SCHEMBL2359774 | 0.70 | KDM4E (0.58) | — | |
| SCHEMBL12571337 | 0.67 | HPGDS (0.41) | GOT1DHODH | |
| SCHEMBL13911004 | 0.67 | GOT1 (0.42) | GOT1DHODH | |
| SCHEMBL18210549 | 0.65 | GOT1 (0.31) | GOT1 | |
| SCHEMBL8992127 | 0.65 | GOT1 (0.31) | GOT1 | |
| SCHEMBL7299303 | 0.65 | KDM4E (0.37) | — | |
| SCHEMBL26766188 | 0.65 | BRD4 (0.36) | GOT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | GOT1 1854/4885DHODH 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.