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Imidazole

Imidazole

SCHEMBL8992494

CCCCc1nc(CCNC(=O)OC(C)(C)C)cn1Cc1ccc(-c2ccccc2C(=O)OC)cc1.c1c[nH]cn1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 1/20 0.45
▸ AGTR2 P50052 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9044845 0.92 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL9255026 0.78 AGTR1 (0.50) AGTR1AGTR2
Hydrochloric Acid SCHEMBL8992382 0.77 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9024785 0.75 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL9044274 0.75 AGT (0.51) AGTR1AGTR2
SCHEMBL7435257 0.73 ACHE (0.54) AGTR1AGTR2
SCHEMBL9045991 0.73 ACHE (0.50) —
SCHEMBL9025617 0.73 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL9025200 0.72 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL9044849 0.71 BRS3 (0.45) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510354-A HYPOTENSIVE AGENTS TANABE SEIYAKU CO., LTD. (JP) 1996-04-23 — — US disclosed