Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992789 | 0.88 | TACR1 (0.40) | TACR1SLC6A3ICAM1SELE | |
| SCHEMBL8992825 | 0.80 | TACR1 (0.37) | TACR1CREBBPEP300ICAM1SELE | |
| SCHEMBL8993283 | 0.78 | TACR1 (0.40) | TACR1CREBBPSLC6A3ICAM1SELE | |
| SCHEMBL8993256 | 0.77 | KDM4C (0.41) | TACR1CREBBPEP300KDM4CICAM1 | |
| SCHEMBL92906 | 0.75 | DRD4 (0.47) | TACR1CREBBPEP300SLC6A3KDM4C | |
| SCHEMBL8992945 | 0.75 | ICAM1 (0.38) | TACR1CREBBPEP300KDM4CICAM1 | |
| SCHEMBL27343854 | 0.75 | CREBBP (0.38) | TACR1CREBBPEP300SLC6A3KDM4C | |
| SCHEMBL25470518 | 0.74 | TACR1 (0.43) | TACR1CREBBPEP300KDM4C | |
| SCHEMBL93016 | 0.74 | SMN1; SMN2 (0.47) | CREBBPKDM4CICAM1SELE | |
| SCHEMBL4184332 | 0.74 | KDM4C (0.47) | TACR1CREBBPEP300KDM4CICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |