Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993283 | 0.90 | TACR1 (0.40) | TACR1CREBBPICAM1SELENPC1 | |
| SCHEMBL8992789 | 0.83 | TACR1 (0.40) | TACR1ICAM1SELENPC1RAB9A | |
| SCHEMBL8992790 | 0.80 | TACR1 (0.43) | TACR1CREBBPICAM1SELEEP300 | |
| SCHEMBL8992804 | 0.78 | DHFR (0.39) | TACR1CREBBPICAM1SELENPC1 | |
| SCHEMBL93016 | 0.74 | SMN1; SMN2 (0.47) | CREBBPICAM1SELEALDH1A1PDE4B | |
| SCHEMBL18410184 | 0.74 | ICAM1 (0.40) | CREBBPICAM1SELEEP300NPC1 | |
| SCHEMBL18410186 | 0.73 | NPC1 (0.40) | CREBBPICAM1SELEALDH1A1EP300 | |
| SCHEMBL27343854 | 0.73 | CREBBP (0.38) | TACR1CREBBPICAM1SELEEP300 | |
| SCHEMBL27287536 | 0.73 | TACR1 (0.43) | TACR1CREBBPEP300NPC1RAB9A | |
| SCHEMBL8632096 | 0.71 | ALDH1A1 (0.50) | TACR1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |