Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 11/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039301 | 0.83 | CXCR4 (0.57) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL14312212 | 0.83 | SIGMAR1 (0.46) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL8038136 | 0.82 | SIGMAR1 (0.62) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL5745082 | 0.82 | SIGMAR1 (0.54) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL8992770 | 0.82 | CXCR4 (0.47) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL14312255 | 0.78 | CXCR4 (0.50) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL10574436 | 0.78 | ALDH1A1 (0.54) | TDP1ALDH1A1LMNA | |
| SCHEMBL8689068 | 0.78 | CXCR4 (0.70) | CXCR4CHRM1KMT2AMEN1CHRM2 | |
| SCHEMBL8038145 | 0.75 | GRIN1 (0.48) | CHRM1HRH3GRIN1GRIN2AGRIN2B | |
| SCHEMBL16656265 | 0.75 | GRIN1 (0.48) | CHRM1HRH3GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292689-B1 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INT BV (NL) | 1996-07-31 | — | — | EP | claimed |
| US-4885363-A | RADIOPHARMACEUTICAL IMAGING; MEDICAL DIAGNOSIS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | claimed |
| EP-0292689-A2 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INTERNATIONAL B.V. (NL) | 1988-11-30 | — | — | EP | claimed |