Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993124 | 0.90 | GPR119 (0.37) | GPR119ALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL8993183 | 0.88 | FYN (0.40) | GPR119FYNKDRALDH1A1HPGD | |
| SCHEMBL8992922 | 0.87 | GPR119 (0.43) | GPR119FYNKDRALDH1A1HPGD | |
| SCHEMBL9221055 | 0.82 | RAB9A (0.38) | GPR119KDRALDH1A1HPGDPOLB | |
| SCHEMBL9221803 | 0.82 | ALDH1A1 (0.44) | KDRALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL8993105 | 0.81 | BRS3 (0.45) | GPR119FYNKDRALDH1A1HPGD | |
| SCHEMBL8993290 | 0.80 | GPR119 (0.41) | GPR119ALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL8993100 | 0.78 | NPC1 (0.53) | GPR119KDRALDH1A1HPGDPOLB | |
| SCHEMBL9220600 | 0.78 | RAB9A (0.38) | KDRALDH1A1HPGDMAPK1POLB | |
| SCHEMBL8992845 | 0.78 | FYN (0.40) | FYNKDRALDH1A1ENPP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |