Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645276 | 0.86 | ACHE (0.48) | ACHEALOX5CYP1A2CYP2C19TAAR1 | |
| SCHEMBL27550232 | 0.84 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL8093981 | 0.84 | TAAR1 (0.46) | ACHEIDO1TAAR1CNR1CNR2 | |
| SCHEMBL8993034 | 0.81 | TAAR1 (0.41) | IDO1TAAR1CNR1CNR2 | |
| SCHEMBL7641239 | 0.80 | MEN1 (0.49) | ACHEALOX5CYP1A2CYP2C19 | |
| SCHEMBL29133193 | 0.80 | ACHE (0.46) | ACHEALOX5CYP1A2CYP2C19IDO1 | |
| SCHEMBL2094961 | 0.80 | TAAR1 (0.48) | ACHECYP2C19IDO1TAAR1 | |
| SCHEMBL11200939 | 0.80 | ESR2 (0.52) | ALOX5 | |
| SCHEMBL18174858 | 0.80 | ACHE (0.64) | ACHECYP1A2IDO1TAAR1GPR84 | |
| SCHEMBL8085589 | 0.79 | LTA4H (0.44) | CYP2C19IDO1TAAR1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |