Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093981 | 0.90 | TAAR1 (0.46) | TAAR1IDO1ESR1ESR2MPO | |
| SCHEMBL8085589 | 0.85 | LTA4H (0.44) | TAAR1IDO1ESR1ESR2 | |
| SCHEMBL8993189 | 0.84 | BCL2 (0.47) | — | |
| SCHEMBL8992935 | 0.83 | TAAR1 (0.41) | TAAR1IDO1MPODAOCNR1 | |
| SCHEMBL10735 | 0.82 | — | — | |
| SCHEMBL8993225 | 0.81 | IDH1 (0.47) | TAAR1IDO1CNR1CNR2 | |
| SCHEMBL8993275 | 0.81 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL8992912 | 0.81 | ACHE (0.48) | TAAR1IDO1CNR1CNR2 | |
| SCHEMBL8992941 | 0.80 | LTA4H (0.49) | TAAR1IDO1ESR1ESR2SLC5A2 | |
| Dimethylamine SCHEMBL2646042 | 0.80 | TAAR1 (0.50) | TAAR1IDO1DAOMAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |