Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18063537 | 0.78 | HTR2C (0.51) | KDM1A | |
| SCHEMBL16388357 | 0.78 | CALM1 (0.48) | LTA4HCHRM2CHRM3 | |
| SCHEMBL14191204 | 0.78 | LTA4H (0.70) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8993057 | 0.78 | LTA4H (0.43) | LTA4HTAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL2099512 | 0.78 | CHRM2 (0.66) | LTA4HCHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL31739258 | 0.76 | LTA4H (0.67) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL2092574 | 0.76 | LTA4H (0.67) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8093299 | 0.75 | MTNR1A (0.57) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL13880096 | 0.75 | MAOB (0.62) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL27950339 | 0.74 | EED (0.50) | CHRM2CHRM1CHRM3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |