Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792504 | 0.83 | MAPK1 (0.42) | LTA4HTAAR1IDO1 | |
| SCHEMBL16388357 | 0.81 | CALM1 (0.48) | LTA4H | |
| SCHEMBL8992923 | 0.78 | LTA4H (0.48) | LTA4HTAAR1SIGMAR1IDO1AGXT | |
| Ammonia Solution, Strong SCHEMBL28621254 | 0.77 | NPC1 (0.37) | LTA4HPNMTTAAR1SIGMAR1CYP3A4 | |
| SCHEMBL1680796 | 0.76 | PNMT (0.39) | PNMTTAAR1SIGMAR1CYP3A4IDO1 | |
| SCHEMBL5431657 | 0.76 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL2093970 | 0.75 | PNMT (0.56) | LTA4HPNMTTAAR1CYP3A4IDO1 | |
| SCHEMBL3300276 | 0.75 | PNMT (0.65) | PNMTTAAR1SIGMAR1CYP3A4IDO1 | |
| SCHEMBL1680744 | 0.75 | NPC1 (0.42) | PNMTTAAR1SIGMAR1CYP3A4IDO1 | |
| SCHEMBL3301781 | 0.73 | PNMT (0.58) | PNMTTAAR1SIGMAR1CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |