Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993377 | 0.85 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL8992924 | 0.84 | CNR2 (0.45) | CNR2PDCD1CD274CA2TSHR | |
| SCHEMBL8993099 | 0.82 | CNR2 (0.44) | CNR1CNR2CA2LMNATP53 | |
| SCHEMBL8993034 | 0.81 | TAAR1 (0.41) | CNR1CNR2 | |
| SCHEMBL8992888 | 0.81 | MEN1 (0.44) | CNR1CNR2PDCD1CD274CA2 | |
| SCHEMBL8992814 | 0.78 | TUBB4A (0.47) | CNR2CA2LMNATSHR | |
| SCHEMBL25703692 | 0.78 | ALDH1A1 (0.49) | CNR1CNR2CA2LMNATP53 | |
| SCHEMBL11292100 | 0.78 | CA2 (0.71) | CA2LMNATP53HPGDTSHR | |
| SCHEMBL20200250 | 0.77 | PDCD1 (0.51) | PDCD1CD274CA2TSHRACHE | |
| SCHEMBL31280574 | 0.77 | PDCD1 (0.51) | PDCD1CD274CA2TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |