Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | LDHB | P07195 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455072 | 0.86 | CALM1 (0.50) | BCL2BCL2L1ALOX5LDHALDHB | |
| SCHEMBL29675199 | 0.86 | CALM1 (0.50) | BCL2BCL2L1ALOX5LDHALDHB | |
| SCHEMBL8087746 | 0.85 | BCL2 (0.45) | BCL2BCL2L1TSHRALOX5LDHA | |
| SCHEMBL8993034 | 0.84 | TAAR1 (0.41) | — | |
| SCHEMBL8993008 | 0.80 | TSHR (0.48) | TSHR | |
| SCHEMBL8065632 | 0.80 | SHBG (0.47) | TSHR | |
| SCHEMBL16010786 | 0.80 | IGF1R (0.45) | BCL2L1TSHR | |
| SCHEMBL10950441 | 0.79 | MAP2K4 (0.41) | TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27550232 | 0.79 | ALOX5 (0.67) | BCL2BCL2L1TSHRALOX5LDHA | |
| SCHEMBL8993225 | 0.79 | IDH1 (0.47) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |