SCHEMBL8993097

SCHEMBL8993097

CCCCCNc1nc(=O)[nH]cc1F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.41
GPR84 Q9NQS5 10/20 0.40
KCNH3 Q9ULD8 1/20 0.38
ELANE P08246 2/20 0.38
TLR8 Q9NR97 2/20 0.38
ADRA2A P08913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490506 0.81 GPR84 (0.41) XDHGPR84ELANE
SCHEMBL18325610 0.77 XDH (0.50) XDH
SCHEMBL2440388 0.75 LMNA (0.52) XDH
SCHEMBL8194684 0.74 USP2 (0.41)
SCHEMBL7063863 0.74 LMNA (0.51) XDH
SCHEMBL7063685 0.74 LMNA (0.51) XDH
SCHEMBL7064550 0.73 LMNA (0.47) XDH
SCHEMBL18325718 0.72 MAT2A (0.37) XDH
SCHEMBL7052872 0.72 ADORA2A (0.44)
SCHEMBL15690949 0.71 TLR8 (0.44) KCNH3TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602478-B1 Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives HOFFMANN LA ROCHE (CH) 1996-07-31 EP disclosed
EP-0602478-A1 Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1994-06-22 EP disclosed