Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608997 | 0.82 | EPHX2 (0.48) | EPHX2ALDH1A1FFAR1KMT2AMEN1 | |
| SCHEMBL8993314 | 0.81 | NPC1 (0.49) | EPHX2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8993272 | 0.81 | NPC1 (0.48) | EPHX2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29561956 | 0.80 | EPHX2 (0.63) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL29401210 | 0.80 | EPHX2 (0.63) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL118052 | 0.80 | EPHX2 (0.63) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL7913189 | 0.77 | EPHX2 (0.59) | EPHX2ALDH1A1PKMKMT2ARAB9A | |
| SCHEMBL608667 | 0.71 | EPHX2 (0.46) | EPHX2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL14879254 | 0.70 | PPARA (0.50) | ALDH1A1POLB | |
| SCHEMBL178731 | 0.70 | KMT2A (0.57) | EPHX2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |