Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993314 | 0.96 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2RECQLEPHX2 | |
| SCHEMBL608997 | 0.93 | EPHX2 (0.48) | NPC1RAB9ASMN1; SMN2RECQLEPHX2 | |
| SCHEMBL118052 | 0.85 | EPHX2 (0.63) | EPHX2KMT2AALDH1A1 | |
| SCHEMBL29401210 | 0.85 | EPHX2 (0.63) | EPHX2KMT2AALDH1A1 | |
| SCHEMBL29561956 | 0.85 | EPHX2 (0.63) | EPHX2KMT2AALDH1A1 | |
| SCHEMBL7913189 | 0.81 | EPHX2 (0.59) | RAB9ASMN1; SMN2EPHX2NPSR1KMT2A | |
| SCHEMBL8993299 | 0.81 | EPHX2 (0.41) | RAB9AEPHX2KMT2AMEN1ALDH1A1 | |
| SCHEMBL608667 | 0.81 | EPHX2 (0.46) | NPC1RAB9ASMN1; SMN2EPHX2CASP1 | |
| SCHEMBL29341843 | 0.76 | EPHX2 (0.62) | EPHX2KMT2A | |
| SCHEMBL29519366 | 0.76 | PLA2G4A (0.45) | NPC1RAB9ASMN1; SMN2CASP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |