Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555228 | 0.69 | SMN1; SMN2 (0.53) | MAPK1HTR2BGAA | |
| SCHEMBL8846878 | 0.69 | SMN1; SMN2 (0.53) | MAPK1HTR2BGAA | |
| SCHEMBL8846872 | 0.69 | SMN1; SMN2 (0.53) | MAPK1HTR2BGAA | |
| SCHEMBL8993511 | 0.69 | SLC6A2 (0.45) | GAA | |
| SCHEMBL8993589 | 0.69 | SLC6A3 (0.51) | TSHRHTTGAA | |
| Hydrochloric Acid SCHEMBL8993466 | 0.68 | SMN1; SMN2 (0.52) | MAPK1HTR2BGAA | |
| SCHEMBL8993503 | 0.66 | ALDH1A1 (0.47) | HTR2CGAA | |
| SCHEMBL8788750 | 0.66 | PBRM1 (0.43) | HTR2CTSHRMAPK1PBRM1KDM1A | |
| SCHEMBL14665736 | 0.66 | HTR2C (0.47) | HTR2CTSHRMAPK1PBRM1KDM1A | |
| SCHEMBL21381496 | 0.64 | GUSB (0.45) | HTR2CPBRM1KDM1AGUSBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |