SCHEMBL8993532

SCHEMBL8993532

CCC1=C(O)C(=O)c2ccc(C)cc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.53
MAOB P27338 2/20 0.53
ELANE P08246 1/20 0.52
NQO1 P15559 3/20 0.48
POR P16435 3/20 0.48
LCK P06239 1/20 0.47
BCL2 P10415 2/20 0.41
MCL1 Q07820 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
XIAP P98170 1/20 0.41
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
USP8 P40818 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9713639 0.84 MAOA (0.47) MAOAMAOBELANENQO1POR
SCHEMBL9353826 0.83 MAOA (0.68) MAOAMAOBELANENQO1POR
SCHEMBL9714008 0.82 XIAP (0.46) NQO1PORMCL1XIAPNPC1
SCHEMBL9713797 0.81 S100A4 (0.50) MAOAMAOBBCL2MCL1XIAP
SCHEMBL24349487 0.80 DHODH (0.56) MAOAMAOBELANENQO1POR
SCHEMBL8781044 0.80 APAF1 (0.60) MAOABCL2MCL1XIAPNPC1
SCHEMBL30003553 0.78 MAOA (0.73) MAOAMAOBELANENQO1POR
SCHEMBL23271984 0.78 MAOA (0.73) MAOAMAOBELANENQO1POR
SCHEMBL182959 0.74 ELANE (0.86) MAOAMAOBELANENQO1POR
SCHEMBL583153 0.74 ELANE (0.86) MAOAMAOBELANENQO1POR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5411675-A Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-02 US claimed
EP-0534436-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1996-08-14 EP disclosed
US-5411675-A Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-02 US disclosed
EP-0534436-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-31 EP disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
EP-0150831-B1 NAPHTHALENE ANTI-PSORIATIC AGENTS SYNTEX (U.S.A.) INC. (US) 1988-08-10 EP disclosed
EP-0150831-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1985-08-07 EP disclosed