Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698516 | 0.80 | PTGS2 (0.54) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6687073 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1MAPK14 | |
| SCHEMBL5698535 | 0.76 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL5698458 | 0.75 | PTGS2 (0.59) | PTGS2PTGS1MAPK14 | |
| SCHEMBL8371975 | 0.72 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL5083262 | 0.71 | MAPK14 (0.57) | PTGS2PTGS1MAPK14 | |
| SCHEMBL17907429 | 0.71 | — | — | |
| SCHEMBL8652478 | 0.70 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8654430 | 0.70 | FGF23 (0.46) | PTGS2MAPK14 | |
| SCHEMBL5694272 | 0.69 | PTGS2 (0.64) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |