Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250810 | 0.84 | TSHR (0.42) | ALDH1A1KDM4EHSD17B10CLCN2MAPT | |
| SCHEMBL8417857 | 0.82 | CYP4F2 (0.45) | ALDH1A1KDM4EHSD17B10MAPTTSHR | |
| SCHEMBL7976218 | 0.81 | PRKAB2 (0.37) | ALDH1A1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8993484 | 0.80 | PRKAB2 (0.36) | ALDH1A1KDM4EPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL8993535 | 0.80 | MAPT (0.45) | ALDH1A1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17063591 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10CLCN2MAPT | |
| SCHEMBL9751862 | 0.78 | MAPK1 (0.36) | ALDH1A1KDM4EPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3436930 | 0.77 | KMT2A (0.41) | ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL6603561 | 0.76 | KDM4E (0.34) | ALDH1A1KDM4EHSD17B10CLCN2TSHR | |
| SCHEMBL24886357 | 0.76 | HPGD (0.45) | ALDH1A1KDM4EHSD17B10MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369803-B2 | Trisubstituted benzoic acid intermediates | ZENECA INC (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0444152-B1 | CERTAIN 2-(2',3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | ZENECA INC (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0444143-B1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | ZENECA INC (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5075497-A | Chemical intermediate for 2-(2,3,4-trisubstitutedbenzoyl)-1,3-cyclohexanedione | ICI AMERICAS, INC. (US) | 1991-12-24 | — | — | US | disclosed |
| US-5073642-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1991-12-17 | — | — | US | disclosed |
| US-5068423-A | Intermediates for herbicides 2-(2,3,4-trisubstituted benzoyl)-1,3-cyclohexanediones | ICI AMERICAS INC. (US) | 1991-11-26 | — | — | US | disclosed |
| US-5047572-A | For 2-*2,3,4-trisubstituted benzoyl)-1,3-cyclohexanedione | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0444152-A1 | CERTAIN 2-(2',3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES. | ICI AMERICA INC (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5001256-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4957538-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-09-18 | — | — | US | disclosed |
| WO-1990005712-A1 | CERTAIN 2-(2',3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | ICI AMERICAS INC. (US) | 1990-05-31 | — | — | WO | disclosed |
| EP-0369803-A1 | Trisubstituted benzoic acid intermediates | ZENECA INC. (US) | 1990-05-23 | — | — | EP | disclosed |