Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994447 | 0.88 | TOP1 (0.60) | MTNR1AMTNR1BABCG2TOP1CYCS | |
| SCHEMBL9910535 | 0.86 | ABCG2 (0.55) | ABCG2TOP1CYCSITKSMN1; SMN2 | |
| SCHEMBL14077524 | 0.84 | ABCG2 (0.54) | MTNR1AMTNR1BABCG2TOP1CYCS | |
| SCHEMBL29408468 | 0.83 | TERT (0.51) | ABCG2TOP1CYCSKDM4EALDH1A1 | |
| SCHEMBL498495 | 0.83 | TERT (0.51) | ABCG2TOP1CYCSKDM4EALDH1A1 | |
| SCHEMBL7241022 | 0.82 | TOP1 (0.58) | ABCG2TOP1CYCSSMN1; SMN2KDM4E | |
| SCHEMBL7258044 | 0.82 | STAT3 (0.49) | MTNR1AMTNR1BABCG2ITKSMN1; SMN2 | |
| SCHEMBL1974241 | 0.80 | TOP1 (0.68) | ABCG2TOP1CYCSITKSMN1; SMN2 | |
| SCHEMBL7261646 | 0.79 | TOP1 (0.60) | ABCG2TOP1CYCSSMN1; SMN2ALDH1A1 | |
| SCHEMBL7239829 | 0.77 | ALDH1A1 (0.54) | ABCG2TOP1CYCSSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| US-6419897-B1 | PORPHYRIN COMPOUNDS | ARIZONA BOARD OF REGENTS | 2002-07-16 | — | — | US | disclosed |
| US-6274729-B1 | PREVENT TISSUE DAMAGE | ARIZONA BOARD OF REGENTS | 2001-08-14 | — | — | US | disclosed |
| US-6207821-B1 | Long-wavelength electromagnetic radiation and photoprotective tumor localizing agents for diagnosis | ARIZONA BOARD OF REGENTS | 2001-03-27 | — | — | US | disclosed |
| US-6183727-B1 | DETECTING A PATHOLOGY OR TARGET TISSUE BY ADMINISTERING A ZINC PHTHALOCYANINE DYES IMAGING MATERIAL AND EXPOSING TO RADIATION WITHOUT DAMAGING THE MAMMALIAN HOST | ARIZONA BOARD OF REGENTS | 2001-02-06 | — | — | US | disclosed |
| WO-1999059641-A1 | USE OF LONG-WAVELENGTH ELECTROMAGNETIC RADIATION OF DIAGNOSIS | ARIZONA BOARD OF REGENTS (US) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | MTNR1A 2928/4885MTNR1B 2441/4885ABCG2 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.