Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058962 | 0.77 | P2RX3 (0.37) | CCR2MEN1POLBKMT2AMAPK14 | |
| SCHEMBL7501169 | 0.74 | NPC1 (0.38) | CCR2CYP2C9POLBS1PR1S1PR5 | |
| SCHEMBL8994485 | 0.74 | KDM4E (0.38) | CCR2MEN1KMT2AMAPK14S1PR1 | |
| SCHEMBL8994475 | 0.72 | MEN1 (0.34) | CCR2APPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8994490 | 0.72 | MAPK14 (0.42) | MEN1KMT2AMAPK14METKDR | |
| SCHEMBL8994492 | 0.70 | MAPK14 (0.46) | MEN1KMT2AMAPK14IDO1LMNA | |
| SCHEMBL8994399 | 0.69 | — | — | |
| SCHEMBL8994380 | 0.68 | POLB (0.34) | MEN1POLBKMT2ALMNAMAPT | |
| SCHEMBL8994415 | 0.67 | ALOX5AP (0.33) | APPCYP3A4PSEN1PSEN2APH1B | |
| SCHEMBL8994385 | 0.67 | POLB (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594941-B1 | N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1996-08-14 | — | — | EP | claimed |