Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | RPA1 | P27694 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505132 | 0.88 | NPC1 (0.39) | NPC1RAB9ADRD2DRD4RPA1 | |
| SCHEMBL9058962 | 0.75 | P2RX3 (0.37) | RPA1CCR2POLBMETKDR | |
| SCHEMBL7509402 | 0.75 | NOTUM (0.39) | CCR2ALDH1A1HPGDMETKDR | |
| SCHEMBL7509428 | 0.75 | DRD2 (0.47) | DRD2DRD4ALDH1A1DRD3KDM4E | |
| SCHEMBL8994474 | 0.74 | CCR2 (0.35) | RPA1CCR2POLBMETKDR | |
| SCHEMBL7503376 | 0.73 | DRD2 (0.40) | DRD2DRD4ALDH1A1DRD3KDM4E | |
| SCHEMBL7507481 | 0.73 | ABL1 (0.37) | CCR2ALDH1A1KDM4EHPGDMET | |
| SCHEMBL8994485 | 0.71 | KDM4E (0.38) | NPC1RAB9ACCR2ALDH1A1KDM4E | |
| SCHEMBL7512356 | 0.70 | SMN1; SMN2 (0.38) | NPC1RAB9ADRD2DRD4ALDH1A1 | |
| SCHEMBL9211282 | 0.70 | MAP3K14 (0.41) | NPC1RAB9ARPA1CCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530515-B1 | Process for the preparation of N-halomethylpyrrole and intermediates | BASF AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0530515-A1 | N-Alkanoylaminomethyl and N-Aroylaminomethyl pyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5130328-A | Lima bean leaves | AMERICAN CYANAMID COMPANY (US) | 1992-07-14 | — | — | US | disclosed |