Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055776 | 0.88 | P2RX3 (0.37) | P2RX3CCR2METKDRGRIA2 | |
| SCHEMBL8994474 | 0.77 | CCR2 (0.35) | CCR2MAPK14METKDRGRIA2 | |
| SCHEMBL7501169 | 0.75 | NPC1 (0.38) | CCR2METKDRRPA1POLB | |
| SCHEMBL8994492 | 0.74 | MAPK14 (0.46) | MAPK14MEN1KMT2AIDO1 | |
| SCHEMBL8994485 | 0.73 | KDM4E (0.38) | CCR2MAPK14ABL1MEN1KMT2A | |
| SCHEMBL9057391 | 0.71 | GRIA2 (0.38) | P2RX3GRIA2GRIA4PTGDR2 | |
| SCHEMBL8994490 | 0.70 | MAPK14 (0.42) | MAPK14METKDRMEN1KMT2A | |
| SCHEMBL8994475 | 0.69 | MEN1 (0.34) | CCR2MAPK14METKDRRPA1 | |
| SCHEMBL7509402 | 0.68 | NOTUM (0.39) | CCR2METKDRABL1MEN1 | |
| SCHEMBL9216319 | 0.67 | MAP3K14 (0.39) | MAPK14METKDRRPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426948-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods | AMERICAN CYANAMID CO (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0426948-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods | AMERICAN CYANAMID COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |