Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994474 | 0.74 | CCR2 (0.35) | SMN1; SMN2S1PR1S1PR5MEN1LMNA | |
| SCHEMBL9058962 | 0.73 | P2RX3 (0.37) | MEN1KMT2AMAPK14CCR2ABL1 | |
| SCHEMBL8994464 | 0.73 | L3MBTL1 (0.34) | KDM4EALDH1A1TSHRMEN1LMNA | |
| SCHEMBL8994481 | 0.72 | MGLL (0.36) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7501169 | 0.71 | NPC1 (0.38) | KDM4EALDH1A1SMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL8994397 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1TSHRMEN1LMNA | |
| SCHEMBL8994492 | 0.69 | MAPK14 (0.46) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL8994395 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2MEN1LMNA | |
| SCHEMBL8994414 | 0.68 | MGLL (0.36) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8994390 | 0.68 | L3MBTL1 (0.35) | KDM4EALDH1A1TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594941-B1 | N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0594941-A1 | N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-05-04 | — | — | EP | claimed |