Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994894 | 0.88 | LTB4R (0.67) | LTB4RLTB4R2PLA2G4BHRH3 | |
| SCHEMBL8994933 | 0.85 | THRB (0.43) | LTB4RLTB4R2ITGB3ITGA2BSRD5A2 | |
| SCHEMBL8995081 | 0.85 | MAOB (0.45) | LTB4R | |
| SCHEMBL8995092 | 0.85 | LTB4R (0.43) | LTB4RGAAL3MBTL1LTB4R2GPR119 | |
| SCHEMBL8995002 | 0.82 | LMNA (0.46) | LTB4RLTB4R2TSHR | |
| SCHEMBL8590612 | 0.81 | LTB4R (0.42) | LTB4RLTB4R2ITGB3ITGA2B | |
| SCHEMBL8590372 | 0.79 | PPARA (0.40) | LTB4R | |
| SCHEMBL8995041 | 0.79 | LTB4R (0.54) | LTB4RGAAL3MBTL1LTB4R2TP53 | |
| SCHEMBL8593369 | 0.78 | FFAR1 (0.40) | LTB4R | |
| SCHEMBL8995034 | 0.77 | LTB4R (0.64) | LTB4RLTB4R2PLA2G4BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | claimed |
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |