Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9139776 | 0.88 | HPGD (0.45) | TP53MEN1KMT2ALTB4RLMNA | |
| SCHEMBL9699605 | 0.85 | PRMT1 (0.56) | MLYCDHTTLTB4RLMNAALDH1A1 | |
| SCHEMBL8995101 | 0.85 | PDE10A (0.51) | HTTTP53TSHRPLA2G4B | |
| Hydrochloric Acid SCHEMBL8593547 | 0.84 | HPGD (0.44) | HTTPLA2G4BMEN1KMT2ALTB4R | |
| SCHEMBL8994945 | 0.84 | LTB4R (0.55) | HTTTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL8994976 | 0.82 | ALDH1A1 (0.52) | MLYCDHTTLTB4RLMNAALDH1A1 | |
| SCHEMBL8748042 | 0.81 | ALDH1A1 (0.50) | MLYCDTP53TSHRPPARAMEN1 | |
| SCHEMBL8748252 | 0.79 | GAA (0.55) | MLYCDTDP1TP53PPARALTB4R | |
| SCHEMBL8748249 | 0.79 | GAA (0.55) | MLYCDTDP1TP53PPARALTB4R | |
| SCHEMBL8995027 | 0.79 | NPC1 (0.54) | HTTTP53TSHRPLA2G4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0518819-B1 | Amidino compounds, their manufacture and use as medicament | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | EP | disclosed |
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |