Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995559 | 0.81 | KMT2A (0.44) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7474092 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8995531 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8995539 | 0.80 | NAMPT (0.45) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL8995542 | 0.80 | NAMPT (0.45) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7418987 | 0.76 | LMNA (0.41) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7384441 | 0.75 | EPHX2 (0.49) | KMT2AALDH1A1HPGDITGB3ITGA2B | |
| SCHEMBL7385683 | 0.75 | EPHX2 (0.54) | KMT2AALDH1A1HPGDITGB3ITGA2B | |
| SCHEMBL7417109 | 0.75 | CASP1 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7414356 | 0.75 | CASP1 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |