Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995577 | 1.00 | MMP12 (0.39) | MMP12MMP13NAMPTFFAR1LMNA | |
| SCHEMBL7423093 | 0.82 | ITGB3 (0.54) | — | |
| SCHEMBL7423099 | 0.82 | ITGB3 (0.54) | — | |
| SCHEMBL7423101 | 0.82 | S1PR2 (0.38) | LMNATSHRPTPN1CYP2D6CYP2C9 | |
| SCHEMBL7417133 | 0.80 | MMP2 (0.50) | MMP12MMP13NAMPTLMNATSHR | |
| SCHEMBL8995579 | 0.79 | ITGB3 (0.41) | LMNATSHRPTPN1 | |
| SCHEMBL7423594 | 0.77 | CTSS (0.55) | KMT2A | |
| SCHEMBL8995569 | 0.77 | CTSS (0.55) | KMT2A | |
| SCHEMBL7423600 | 0.77 | CTSS (0.55) | KMT2A | |
| SCHEMBL7421070 | 0.75 | ITGB3 (0.55) | NAMPTLMNATSHRPTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |