Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388238 | 0.84 | CA2 (0.48) | CA2CA12CA1CA9LMNA | |
| SCHEMBL606177 | 0.84 | CA2 (0.48) | CA2CA12CA1CA9LMNA | |
| SCHEMBL8995742 | 0.82 | LDHA (0.55) | CA2CA12CA1CA9LMNA | |
| SCHEMBL8995744 | 0.82 | LDHA (0.55) | CA2CA12CA1CA9LMNA | |
| SCHEMBL7128561 | 0.81 | ALDH1A1 (0.50) | LMNAALDH1A1LDHAKDM4EMEN1 | |
| SCHEMBL2688605 | 0.79 | ALDH1A1 (0.64) | CA2CA12CA1CA9LMNA | |
| SCHEMBL13792083 | 0.77 | ESR1 (0.48) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL3993833 | 0.77 | ESR1 (0.48) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL5114907 | 0.76 | CA2 (0.59) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL358270 | 0.76 | HSD17B2 (0.54) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492830-A | CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY | GENZYME CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |