Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995742 | 1.00 | LDHA (0.55) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL31513490 | 0.88 | TSHR (0.60) | ALDH1A1MTNR1AMTNR1BHTTLMNA | |
| SCHEMBL8407767 | 0.88 | TSHR (0.60) | ALDH1A1MTNR1AMTNR1BHTTLMNA | |
| SCHEMBL8974036 | 0.85 | LDHA (0.57) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL24534351 | 0.83 | ALDH1A1 (0.60) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL6339568 | 0.83 | ALDH1A1 (0.60) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL6339567 | 0.83 | ALDH1A1 (0.60) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL29658682 | 0.83 | ALDH1A1 (0.60) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL29658681 | 0.83 | ALDH1A1 (0.60) | LDHAALDH1A1CA2MTNR1AMTNR1B | |
| SCHEMBL8995741 | 0.82 | CA2 (0.49) | LDHAALDH1A1CA2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492830-A | CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY | GENZYME CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |