Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485512 | 0.91 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL6511114 | 0.90 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL9007854 | 0.87 | GAA (0.51) | ALDH1A1GAAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8995839 | 0.84 | TDP1 (0.52) | ALDH1A1GAASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL10579985 | 0.84 | HSD17B3 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4688387 | 0.82 | HTR7 (0.51) | ALDH1A1GAAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8591084 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBCTDSP1L3MBTL1 | |
| Hydrogen Peroxide SCHEMBL29219018 | 0.81 | LMNA (0.56) | ALDH1A1SMN1; SMN2L3MBTL1CES2CES1 | |
| SCHEMBL266279 | 0.81 | LMNA (0.56) | ALDH1A1SMN1; SMN2L3MBTL1CES2CES1 | |
| SCHEMBL8995775 | 0.81 | TSHR (0.46) | ALDH1A1KDM4EPOLBKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | claimed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-110552018-B | Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization | 广西师范大学 | 2021-03-05 | — | — | CN | disclosed |
| CN-108440291-B | Method for dehydrogenation and self-coupling of 1, 3-dicarbonyl compound under catalysis of visible light | 南京工业大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-110552018-A | Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization | UNIV GUANGXI NORMAL | 2019-12-10 | — | — | CN | disclosed |
| CN-110437244-A | A kind of synthetic method of Frutinone class compound | UNIV YANGTZE | 2019-11-12 | — | — | CN | disclosed |
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | disclosed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105418596-A | 1-[3-butyl-1(3H)-isobenzofuranone-6-yl]-1H-pyrazol-5(4H)-one derivative as well as preparation method and pharmaceutical application | UNIV WUHAN SCIENCE & TECH | 2016-03-23 | — | — | CN | disclosed |
| CN-105018399-A | Screening method of beta-carbonyl carboxylic ester reductase | UNIV CHANGZHOU | 2015-11-04 | — | — | CN | disclosed |
| CN-101918497-B | Pigment composition for red color filter, method for producing the same, colored composition using the same, and color filter | TOYO INK MFG CO | 2014-05-28 | — | — | CN | disclosed |
| US-5096920-A | Liver disorders | KALI-CHEMIE PHARMA GMBH (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |
| US-5002951-A | 2-amino-5-halo-4-pyrimidinol for bactericides and antiprotozoa agent | THE UPJOHN COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4665077-A | IMMUNOREGULATORY AGENTS | THE UPJOHN COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| CN-85106626-A | The preparation of 4-amino-2-phenyl-quinoline | — | 1987-03-25 | — | — | CN | disclosed |
| US-4619933-A | 6-aryl pyrimidines for treating aplastic anemia | THE UPJOHN COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4543248-A | Method for immunoregulation with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4507302-A | Method for treating arthritis with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-4222739-A | Certain bis(phenyl)-benzodifurans | CIBA-GEIGY CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |