Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655841 | 0.86 | HTR1A (0.52) | DPP7HPGDMAPTNTSR1ALDH1A1 | |
| SCHEMBL8995907 | 0.81 | HPGD (0.56) | HPGDRAB9APOLBMAPTALDH1A1 | |
| SCHEMBL22397201 | 0.75 | POLB (0.53) | POLBLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7977861 | 0.73 | GAA (0.47) | DPP7POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8995919 | 0.73 | NPC1 (0.49) | DPP7RAB9APOLBHTTNPC1 | |
| SCHEMBL8995910 | 0.73 | HTR1A (0.64) | NTSR1UTS2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8761484 | 0.72 | HTR1A (0.53) | DPP7HPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL8405067 | 0.72 | HTR1A (0.53) | DPP7HPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL28872797 | 0.72 | DPP7 (0.44) | DPP7NTSR1ALDH1A1UTS2RDPP8 | |
| SCHEMBL370424 | 0.71 | DPP7 (0.48) | DPP7HPGDRAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541179-A | Tropon-2-one piperazine carboxamides as serotonergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |