Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995915 | 0.81 | DPP7 (0.49) | HPGDALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL8655841 | 0.79 | HTR1A (0.52) | HPGDKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL17206663 | 0.79 | ALDH1A1 (0.59) | HPGDL3MBTL1ALDH1A1TP53MAPT | |
| SCHEMBL2237437 | 0.77 | ALDH1A1 (0.56) | HPGDL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL17206651 | 0.77 | HPGD (0.50) | HPGDL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL2240734 | 0.77 | HPGD (0.50) | HPGDL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL2235599 | 0.75 | MMP1 (0.53) | HPGDL3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL8995919 | 0.75 | NPC1 (0.49) | L3MBTL1KMT2ARAB9APOLBMEN1 | |
| SCHEMBL2238451 | 0.75 | ALDH1A1 (0.48) | HPGDALDH1A1TP53MAPTKMT2A | |
| SCHEMBL8995908 | 0.75 | HTR1A (0.64) | HPGDL3MBTL1KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541179-A | Tropon-2-one piperazine carboxamides as serotonergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |