SCHEMBL237914

SCHEMBL237914

C=C1CC(=O)N(c2ccc(N3C(=O)CC(=C)C3=O)cc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.44
TLR9 Q9NR96 2/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 7/20 0.43
MEN1 O00255 6/20 0.43
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
RAB9A P51151 1/20 0.37
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA9 Q16790 2/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894350 0.90 MEN1 (0.54) KMT2AMEN1MAPTSMN1; SMN2MGLL
SCHEMBL2983688 0.90 GAA (0.57) GAATLR9KMT2AMEN1MAPT
SCHEMBL4443303 0.90 MGLL (0.56) PKMKMT2AMEN1HPGDFAAH
SCHEMBL225820 0.90 GAA (0.58) GAATLR9PKMKMT2AMEN1
SCHEMBL7932608 0.89 MGLL (0.48) GAATLR9PKMKMT2AMEN1
SCHEMBL12317338 0.87 TRIM24 (0.42) GAATLR9PKMKMT2AMEN1
SCHEMBL22728447 0.86 BCHE (0.47) GAATLR9PKMKMT2AMEN1
SCHEMBL12268781 0.84 ADAM17 (0.50) GAATLR9KMT2AMEN1MAPT
SCHEMBL9069523 0.84 CASP6 (0.47) GAATLR9PKMKMT2AMEN1
SCHEMBL8995947 0.83 HSP90AA1 (0.54) GAATLR9PKMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP claimed
US-20240043636-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY COMPOSITE MATERIALS AMERICA, INC. (US) 2024-02-08 US disclosed
US-20240010805-A1 BMI RESIN FORMULATION FOR CARBON FIBER REINFORCED COMPOSITE MATERIAL, METHOD FOR MAKING IT AND BMI PREPREG TORAY COMPOSITE MATERIALS AMERICA, INC. (US) 2024-01-11 US disclosed
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed
EP-4255968-A1 BMI RESIN FORMULATION FOR CARBON FIBER REINFORCED COMPOSITE MATERIAL, METHOD FOR MAKING IT AND BMI PREPREG Toray Composite Materials America, Inc. (US) 2023-10-11 EP disclosed
EP-4255967-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Composite Materials America, Inc. (US) 2023-10-11 EP disclosed
WO-2022120053-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY COMPOSITE MATERIALS AMERICA, INC. (US) 2022-06-09 WO disclosed
WO-2022120049-A1 BMI RESIN FORMULATION FOR CARBON FIBER REINFORCED COMPOSITE MATERIAL, METHOD FOR MAKING IT AND BMI PREPREG TORAY COMPOSITE MATERIALS AMERICA, INC. (US) 2022-06-09 WO disclosed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
US-4962161-A BISMALEIMIDE OR POLYMALEIMIDE AND ETHER DERIVATIVE OF ALKENYLPHENOL HERCULES INCORPORATED (US) 1990-10-09 US disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
US-4874828-A AEROSPACE HERCULES INCORPORATED (US) 1989-10-17 US disclosed
EP-0313863-A2 Heat resistant thermosetting phosphazene-imide copolymers HERCULES INCORPORATED (US) 1989-05-03 EP disclosed
EP-0304009-A1 Thermosettable resin compositions HERCULES INCORPORATED (US) 1989-02-22 EP disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed
US-4076697-A FROM POLYIMIDES AND POLYCARBOXYLIC ACIDS IN THE PRESENCE OF AN AMINE CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed
US-4066621-A CURABLE MIXTURES BASED ON POLYIMIDES OF UNSATURATED DICARBOXYLIC ACIDS AND INDOLE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4038251-A PROCESS FOR THE MANUFACTURE OF POLYADDITION PRODUCTS CONTAINING IMIDE GROUPS BY REACTION OF POLYMALEIMIDES WITH POLYHYDRIC PHENOLS USING AMINE CATALYST CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KDM5C, DHX15, KDM5A GAA 1500/4885TLR9 1070/4885PKM 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.