Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996467 | 0.85 | KDM4E (0.53) | ELANEKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL8996388 | 0.80 | ALDH1A1 (0.52) | ELANEKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL16689153 | 0.76 | SMN1; SMN2 (0.59) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL11314713 | 0.75 | KDM4E (0.54) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL8996330 | 0.75 | AMY1A (0.54) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL6510175 | 0.74 | KDM4E (0.62) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL2245507 | 0.73 | KDM4E (0.68) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL25311250 | 0.73 | MEN1 (0.51) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL30472181 | 0.73 | MEN1 (0.51) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL9878296 | 0.71 | ELANE (0.60) | ELANEKDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |