SCHEMBL8997129

SCHEMBL8997129

Cc1cccc(CCCCO)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
ALOX5 P09917 1/20 0.45
PTGS2 P35354 1/20 0.45
TRPA1 O75762 1/20 0.43
TYR P14679 1/20 0.40
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
IAPP P10997 2/20 0.37
EGFR P00533 1/20 0.37
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8405872 0.94 ALDH1A1 (0.50) ALDH1A1ALOX5PTGS2TRPA1TYR
SCHEMBL8400520 0.90 ALDH1A1 (0.54) ALDH1A1ALOX5PTGS2TRPA1TYR
SCHEMBL1917835 0.86 ALDH1A1 (0.54) ALDH1A1ALOX5PTGS2TRPA1GABRA1
SCHEMBL9153692 0.86 ALOX5 (0.47) ALOX5PTGS2TYRGABRA1GABRB2
SCHEMBL1022161 0.85 ALOX5 (0.62) ALDH1A1ALOX5PTGS2TYRIAPP
SCHEMBL7171678 0.83 ALOX5 (0.60) ALDH1A1ALOX5PTGS2TYRKDM4E
SCHEMBL7178199 0.83 ALOX5 (0.60) ALDH1A1ALOX5PTGS2TYRKDM4E
SCHEMBL10475510 0.83 ALOX5 (0.60) ALDH1A1ALOX5PTGS2TYRKDM4E
SCHEMBL8591315 0.83 ALOX5 (0.60) ALDH1A1ALOX5PTGS2TYRKDM4E
SCHEMBL28362575 0.83 ALOX5 (0.60) ALDH1A1ALOX5PTGS2TYRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530442-B1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEM CORP (JP) 1996-09-04 EP claimed
US-5266673-A Compatibilizer for polymer blends and alloys MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-30 US claimed
EP-0530442-A1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-10 EP claimed
EP-0530442-B1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEM CORP (JP) 1996-09-04 EP disclosed
US-5266673-A Compatibilizer for polymer blends and alloys MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-30 US disclosed
EP-0530442-A1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-10 EP disclosed
EP-0517017-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1992-12-09 EP disclosed