Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807688 | 0.81 | ALDH1A1 (0.58) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL3397595 | 0.81 | ALPL (0.58) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL11802373 | 0.81 | ALDH1A1 (0.58) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL16756501 | 0.81 | ALPL (0.58) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL899731 | 0.81 | MLKL (0.77) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL16756243 | 0.81 | ALPL (0.58) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL3397586 | 0.81 | ALDH1A1 (0.62) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL30601597 | 0.81 | MLKL (0.77) | ALDH1A1IDO1POLBALPLMAPK1 | |
| SCHEMBL18689830 | 0.80 | ALDH1A1 (0.62) | ALDH1A1POLBMLKLGAAKMT2A | |
| SCHEMBL7033890 | 0.80 | MAPT (0.56) | ALDH1A1POLBMAPK1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063090-B2 | Mineralocorticoid receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2011-11-22 | — | — | US | claimed |
| US-20100069452-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2010-03-18 | — | — | US | claimed |
| CN-106802536-B | Transfer material, method for producing same, laminate, and method for producing same | 富士胶片株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-110716668-A | Transfer film, laminate, method for producing same, and use thereof | 富士胶片株式会社 | 2020-01-21 | — | — | CN | disclosed |
| US-10192651-B2 | Transfer material, method of manufacturing transfer material, laminated body, method of manufacturing laminated body, method of manufacturing capacitance-type input device, and method of manufacturing image display device | FUJIFILM CORPORATION (JP) | 2019-01-29 | — | — | US | disclosed |
| US-10157695-B2 | — | — | 2018-12-18 | — | — | US | disclosed |
| US-10059087-B2 | Transfer film, method for manufacturing transfer film, laminate, method for manufacturing laminate, capacitive input device, and image display device | FUJIFILM CORPORATION (JP) | 2018-08-28 | — | — | US | disclosed |
| CN-106802536-A | Transfer materials and its manufacture method, layered product and its manufacture method | 富士胶片株式会社 | 2017-06-06 | — | — | CN | disclosed |
| US-20170154704-A1 | TRANSFER MATERIAL, METHOD OF MANUFACTURING TRANSFER MATERIAL, LAMINATED BODY, METHOD OF MANUFACTURING LAMINATED BODY, METHOD OF MANUFACTURING CAPACITANCE-TYPE INPUT DEVICE, AND METHOD OF MANUFACTURING IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2017-06-01 | — | — | US | disclosed |
| CN-106660309-A | Transfer film, method for manufacturing transfer film, laminate, method for manufacturing laminate, capacitance-type input device, and image display device | 富士胶片株式会社 | 2017-05-10 | — | — | CN | disclosed |
| US-20170095999-A1 | TRANSFER FILM, METHOD FOR MANUFACTURING TRANSFER FILM, LAMINATE, METHOD FOR MANUFACTURING LAMINATE, CAPACITIVE INPUT DEVICE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2017-04-06 | — | — | US | disclosed |
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-5098920-A | Hypotensive agents and treatment of congestive heart failure | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | disclosed |
| WO-1992004335-A2 | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992002257-A2 | RENAL-SELECTIVE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-02-20 | — | — | WO | disclosed |
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |
| WO-1991018888-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069452-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | NR3C2, MC2R, NR3C1 | ALDH1A1 2362/4885IDO1 2516/4885POLB 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.