Styrene

Styrene

SCHEMBL8997412

C=C(C)C(=O)Oc1ccccc1C.C=Cc1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
PPARG P37231 1/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
BCHE P06276 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
NOTUM Q6P988 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650229 0.87 ELANE (0.50) ELANEALDH1A1TSHRPPARGATM
Styrene SCHEMBL28776566 0.83 THRB (0.46) ALDH1A1TSHRPPARGMAPTATM
Styrene SCHEMBL28234664 0.83 ELANE (0.59) ELANEALDH1A1TSHRMAPTATM
Styrene SCHEMBL544781 0.83 ELANE (0.59) ELANEALDH1A1TSHRMAPTATM
Styrene SCHEMBL8073704 0.83 ELANE (0.64) ELANEALDH1A1TSHRMAPTATM
Styrene SCHEMBL8997402 0.81 ELANE (0.57) ELANEALDH1A1TSHRPPARGMAPT
Styrene SCHEMBL209287 0.80 ELANE (0.56) ELANEALDH1A1TSHRMAPTATM
Styrene SCHEMBL6426317 0.79 ALDH1A1 (0.50) ELANEALDH1A1TSHRMAPTTDP1
Styrene SCHEMBL9639818 0.79 ALDH1A1 (0.54) ELANEALDH1A1TSHRMAPTTDP1
Styrene SCHEMBL678464 0.79 ALDH1A1 (0.54) ELANEALDH1A1TSHRMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458082-B1 Encapsulated toner compositions XEROX CORP (US) 1996-09-04 EP claimed