Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.39 |
| ▸ | THRA | P10827 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273788 | 0.93 | THRB (0.36) | THRBTHRAALDH1A1GAACAPN1 | |
| SCHEMBL8745450 | 0.83 | KMT2A (0.45) | THRBTHRAALDH1A1ALOX15FPR2 | |
| SCHEMBL8997457 | 0.78 | THRB (0.38) | THRBTHRA | |
| SCHEMBL7275728 | 0.75 | THRB (0.36) | THRBTHRAALDH1A1GAACAPN1 | |
| SCHEMBL7281978 | 0.74 | THRA (0.53) | THRBTHRAALDH1A1GAACAPN1 | |
| SCHEMBL7281471 | 0.73 | KDM4E (0.33) | THRBTHRAALDH1A1GAACAPN1 | |
| SCHEMBL7273784 | 0.73 | THRB (0.35) | THRBTHRA | |
| SCHEMBL8331570 | 0.72 | ALDH1A1 (0.37) | THRBTHRAALDH1A1GAA | |
| SCHEMBL8745406 | 0.71 | KMT2A (0.48) | THRBTHRAALDH1A1ALOX15FPR2 | |
| SCHEMBL8745433 | 0.71 | KMT2A (0.48) | THRBTHRAALDH1A1ALOX15FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728482-A2 | Use of hcp specific compounds to enhance erythropoiesis | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |