Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997600 | 0.84 | SYK (0.40) | RPS6KA1LMNAITGA4ITGB7CYP1A2 | |
| SCHEMBL8583595 | 0.84 | GHSR (0.44) | GHSRRPS6KA1LMNASMN1; SMN2MTNR1A | |
| SCHEMBL8997596 | 0.83 | GHSR (0.35) | GHSRLMNAMTNR1AMTNR1BPRMT5 | |
| SCHEMBL8997604 | 0.82 | GHSR (0.34) | GHSR | |
| SCHEMBL8567143 | 0.82 | CA1 (0.39) | GHSRMAPT | |
| SCHEMBL8573147 | 0.82 | CYP3A4 (0.37) | GHSRADRB2HTR1ACTSSCTSK | |
| SCHEMBL8575729 | 0.82 | CA1 (0.39) | GHSRMAPT | |
| SCHEMBL8560312 | 0.81 | GHSR (0.39) | GHSRMTNR1AMTNR1BDPP8DPP9 | |
| SCHEMBL8559137 | 0.81 | GHSR (0.39) | GHSRMTNR1AMTNR1BDPP8DPP9 | |
| SCHEMBL8997619 | 0.80 | GHSR (0.35) | GHSRLMNAMTNR1AMTNR1BPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |