Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 9/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997593 | 0.89 | ALDH1A1 (0.35) | SYKCA1CA2ACHEKCNA5 | |
| SCHEMBL8581093 | 0.87 | GHSR (0.40) | SYKCA1CA2ACHEKCNA5 | |
| SCHEMBL8575729 | 0.87 | CA1 (0.39) | SYKCA1CA2ACHEMAPT | |
| SCHEMBL8567143 | 0.87 | CA1 (0.39) | SYKCA1CA2ACHEMAPT | |
| SCHEMBL8997625 | 0.84 | GHSR (0.37) | ITGA4ITGB7RPS6KA1MAPTLMNA | |
| SCHEMBL8997648 | 0.83 | SYK (0.38) | SYKCA1CA2ACHE | |
| SCHEMBL8997699 | 0.81 | CA1 (0.36) | SYKCA1CA2ACHEALDH1A1 | |
| SCHEMBL8561422 | 0.80 | CTSV (0.36) | CA1CA2ACHEITGA4ITGB7 | |
| SCHEMBL8997631 | 0.80 | SYK (0.35) | SYKCA1CA2ACHE | |
| SCHEMBL8561322 | 0.79 | SYK (0.40) | SYKCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |