Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997628 | 0.92 | CA1 (0.34) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997699 | 0.87 | CA1 (0.36) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997631 | 0.86 | SYK (0.35) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8561322 | 0.86 | SYK (0.40) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8575729 | 0.86 | CA1 (0.39) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8567143 | 0.86 | CA1 (0.39) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997600 | 0.83 | SYK (0.40) | SYKCA1CA2ACHE | |
| SCHEMBL8997778 | 0.83 | MEN1 (0.40) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997594 | 0.82 | SYK (0.40) | SYKCA1CA2ACHE | |
| SCHEMBL8997810 | 0.82 | P2RY1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |