Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997810 | 0.92 | P2RY1 (0.39) | — | |
| SCHEMBL8997594 | 0.90 | SYK (0.40) | SYKCA1CA2ACHEPSMB5 | |
| SCHEMBL8997648 | 0.86 | SYK (0.38) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997716 | 0.85 | GHSR (0.33) | GHSRPRMT5WDR77CASP3IDO1 | |
| SCHEMBL8997804 | 0.83 | P2RY1 (0.37) | SYKCTSK | |
| SCHEMBL8567143 | 0.82 | CA1 (0.39) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8575729 | 0.82 | CA1 (0.39) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997699 | 0.82 | CA1 (0.36) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8997628 | 0.81 | CA1 (0.34) | SYKCA1CA2ACHEGHSR | |
| SCHEMBL8561322 | 0.81 | SYK (0.40) | SYKCA1CA2ACHEGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |